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Basler
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Spafas Inc
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Spafas Inc
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Charles River Laboratories
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Image Search Results
Journal: Journal of immunology (Baltimore, Md. : 1950)
Article Title: Regulation and Dynamics of Interferon-beta Expression Revealed with a Knockin Reporter Mouse
doi: 10.4049/jimmunol.2400227
Figure Lengend Snippet: (A) BMDMs from I-TOMCAT KI/+ Rosa26 FSF-eYFP/+ mice treated with 10μg/mL DMXAA for 6, 24, 48, and 72hrs. (B) BMDMs from I-TOMCAT KI/KI, I-TOMCAT KI/KI Sting −/− , and I-TOMCAT KI/KI Mavs −/− mice. Treated for 6hrs with 4μg/mL CT-DNA, 4μg/mL ISD-45, 50 HAU/mL SeV Cantell strain (Charles River Lot# 7Y200221), or lipofectamine alone. (C) RT-PCR quantification of Ifnb1 mRNA transcript of BMDM from I-TOMCAT KI/KI, I-TOMCAT KI/KI Sting −/− , and I-TOMCAT KI/KI Mavs −/− mice treated for 6hrs as in (B). Statistics calculated by ordinary one-way ANOVA with Tukey’s Test. *p<0.05 **p<0.01 ****p<0.0001.
Article Snippet: Treated for 6hrs with 4μg/mL CT-DNA, 4μg/mL ISD-45, 50 HAU/mL
Techniques: Activation Assay, Expressing, Reverse Transcription Polymerase Chain Reaction